Construction of Multiple Hepatic Lobule like 3D Vascular Networks by Manipulating Magnetic Tweezers toward Tissue Engineering
Eunhye Kim,Masaru Takeuchi,Taro Kozuka,Takuto Nomura,Akihiko Ichikawa,Yasuhisa Hasegawa,Qiang Huang,Toshio Fukuda,Eunhye Kim,Masaru Takeuchi,Taro Kozuka,Takuto Nomura,Akihiko Ichikawa,Yasuhisa Hasegawa,Qiang Huang,Toshio Fukuda
In this paper, we have constructed actively perfusable multiple hepatic lobule-like vascular networks in a 3D cellular structure by using magnetic tweezers. Without well-organized channel networks, cells in a large 3D tissue cannot receive nutrients and oxygen from the channel, and therefore, the cells will be dead after few days. To construct well-organized channel networks, we fabricated a hepat...
