Acoustic and magnetic hybrid actuated immune cell robot for target and kill cancer cells

Xue Bai,Wei Zhang,Yuguo Dai,Yueying Wang,Hongyan Sun,Lin Feng,Xue Bai,Wei Zhang,Yuguo Dai,Yueying Wang,Hongyan Sun,Lin Feng

Macrophage immunotherapy is a promising clinical approach to treat cancer. However, low targeting efficiency severely limits the immunotherapeutic effect of macrophages. Here, we report a unique macrophage robot that can target and kill cancer cells using a combination of external acoustic and magnetic fields. First, the inactive macrophages (Mø) are magnetized by endocytosis of the $\gamma$-Fe2O3...