Development of a Stereo-vision based High-throughput Robotic System for Mouse Tail Vein Injection

Tianyi Ko,Koichi Nishiwaki,Koji Terada,Yusuke Tanaka,Shun Mitsumata,Ryuichi Katagiri,Junko Taketo,Naoshi Horiba,Hideyoshi Igata,Kazue Mizuno,Tianyi Ko,Koichi Nishiwaki,Koji Terada,Yusuke Tanaka,Shun Mitsumata,Ryuichi Katagiri,Junko Taketo,Naoshi Horiba,Hideyoshi Igata,Kazue Mizuno

In this paper, we present a robotic device for mouse tail vein injection. We propose a mouse holding mechanism to realize vein injection without anesthetizing the mouse, which consists of a tourniquet, vacuum port, and adaptive tail-end fixture. The position of the target vein in 3D space is reconstructed from a high-resolution stereo vision. The vein is detected by a simple but robust vein line d...