Reconfigurable Magnetic Microswarm for Thrombolysis under Ultrasound Imaging

Qianqian Wang,Ben Wang,Jiangfan Yu,Kathrin Schweizer,Bradley J. Nelson,Li Zhang,Qianqian Wang,Ben Wang,Jiangfan Yu,Kathrin Schweizer,Bradley J. Nelson,Li Zhang

We propose thrombolysis using a magnetic nanoparticle microswarm with tissue plasminogen activator (tPA) under ultrasound imaging. The microswarm is generated in blood using an oscillating magnetic field and can be navigated with locomotion along both the long and short axis. By modulating the input field, the aspect ratio of the microswarm can be reversibly tuned, showing the ability to adapt to ...